Anti-DRD2 nanobody [SAA1361] (STJN000151)

SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
STJN000151
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General Information

Short DescriptionAlpaca monoclonal nanobody anti-D (2 Dopamine Receptor is suitable for use in ELISA research applications.
ApplicationsELISA
HostAlpaca
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSAA1361
IsotypeVHH-8His-Cys-tag
ConjugationUnconjugated
Concentration1 mg/mL
PurificationPurified by Nickel column.
Formulation0.01M PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Target Information

Gene SymbolDRD2
Gene ID1813
Uniprot IDDRD2_HUMAN

Additional Info

Post Translational Modifications Palmitoylated. Palmitoylation which is required for proper localization to the plasma membrane and stability of the receptor could be carried on by ZDHHC4, ZDHHC3 and ZDHHC8.
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5.
Protein Name D(2 Dopamine Receptor
Dopamine D2 Receptor
Database Links Reactome: R-HSA-390651
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Golgi Apparatus Membrane
Alternative Nanobody Names Anti-D(2 Dopamine Receptor nanobody
Anti-Dopamine D2 Receptor nanobody
Anti-DRD2 nanobody

Information sourced from Uniprot.org

Citations

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