Anti-DPYD antibody (861-874 aa) [R02-7C8] (STJA0011251)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human DPD
General Information
| Short Description | Rabbit monoclonal anti-DPD (861-874 aa) for use in WB, IHC-F, IHC-P, ICC and IF in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-7C8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4ยฐC short term. Aliquot and store at-20ยฐC long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DPYD |
| Gene ID | 1806 |
| Uniprot ID | DPYD_HUMAN |
| Immunogen | A synthetic peptide of human DPD |
| Immunogen Region | 861-874 aa |
Additional Info
| Tissue Specificity | Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells. |
| Function | Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. |
| Protein Name | Dihydropyrimidine Dehydrogenase Nadp(+DhpdhaseDpdDihydrothymine DehydrogenaseDihydrouracil Dehydrogenase |
| Database Links | Reactome: R-HSA-73621 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Dihydropyrimidine Dehydrogenase Nadp(+ antibodyAnti-Dhpdhase antibodyAnti-Dpd antibodyAnti-Dihydrothymine Dehydrogenase antibodyAnti-Dihydrouracil Dehydrogenase antibodyAnti-DPYD antibody |
Information sourced from Uniprot.org