Host: | Rabbit |
Applications: | WB/IHC-F/IHC-P/ICC/IF |
Reactivity: | Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-DPD (861-874 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry and Immunofluorescence research applications. |
Clonality : | Monoclonal |
Clone ID : | R02-7C8 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Purification: | Affinity Purified |
Concentration: | 0.3 mg/ml |
Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Gene Symbol: | DPYD |
Gene ID: | 1806 |
Uniprot ID: | DPYD_HUMAN |
Immunogen Region: | 861-874 aa |
Immunogen: | A synthetic peptide of human DPD |
Tissue Specificity | Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells. |
Function | Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. |
Protein Name | Dihydropyrimidine Dehydrogenase Nadp(+DhpdhaseDpdDihydrothymine DehydrogenaseDihydrouracil Dehydrogenase |
Database Links | Reactome: R-HSA-73621 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Dihydropyrimidine Dehydrogenase Nadp(+ antibodyAnti-Dhpdhase antibodyAnti-Dpd antibodyAnti-Dihydrothymine Dehydrogenase antibodyAnti-Dihydrouracil Dehydrogenase antibodyAnti-DPYD antibody |
Information sourced from Uniprot.org