Anti-DPH1 antibody (STJA0009092)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human OVCA1
General Information
| Short Description | Rabbit polyclonal anti-2-3-amino-3-carboxypropylhistidine synthase subunit 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DPH1 |
| Gene ID | 1801 |
| Uniprot ID | DPH1_HUMAN |
| Immunogen | Synthesized peptide derived from human OVCA1 |
| Specificity | This antibody detects endogenous levels of OVCA1 at Human, Mouse |
Additional Info
| Function | Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Acts as a tumor suppressor. |
| Protein Name | 2-(3-Amino-3-Carboxypropylhistidine Synthase Subunit 1Diphthamide Biosynthesis Protein 1Diphtheria Toxin Resistance Protein 1Ovarian Cancer-Associated Gene 1 ProteinS-Adenosyl-L-Methionine -L-Histidine 3-Amino-3-Carboxypropyltransferase 1 |
| Database Links | Reactome: R-HSA-5358493 |
| Cellular Localisation | NucleusCytoplasmPunctatePrimarily Perinuclear Localization |
| Alternative Antibody Names | Anti-2-(3-Amino-3-Carboxypropylhistidine Synthase Subunit 1 antibodyAnti-Diphthamide Biosynthesis Protein 1 antibodyAnti-Diphtheria Toxin Resistance Protein 1 antibodyAnti-Ovarian Cancer-Associated Gene 1 Protein antibodyAnti-S-Adenosyl-L-Methionine -L-Histidine 3-Amino-3-Carboxypropyltransferase 1 antibodyAnti-DPH1 antibodyAnti-DPH2L antibodyAnti-DPH2L1 antibodyAnti-OVCA1 antibody |
Information sourced from Uniprot.org