Anti-DOK6 antibody (111-160 aa) (STJ92765)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human DOK6 at the amino acid range 111-160
General Information
| Short Description | Rabbit polyclonal anti-Docking protein 6 (111-160 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DOK6 |
| Gene ID | 220164 |
| Uniprot ID | DOK6_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human DOK6 at the amino acid range 111-160 |
| Immunogen Region | 111-160 aa |
| Specificity | Dok-6 Polyclonal Antibody detects endogenous levels of Dok-6 protein. |
Additional Info
| Post Translational Modifications | On Ret activation, phosphorylated on one or more C-terminal tyrosine residues by an Src family kinase. |
| Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance. |
| Protein Name | Docking Protein 6Downstream Of Tyrosine Kinase 6 |
| Database Links | Reactome: R-HSA-8853659 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Docking Protein 6 antibodyAnti-Downstream Of Tyrosine Kinase 6 antibodyAnti-DOK6 antibodyAnti-DOK5L antibody |
Information sourced from Uniprot.org