| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Docking protein 6 (111-160 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DOK6 |
| Gene ID: | 220164 |
| Uniprot ID: | DOK6_HUMAN |
| Immunogen Region: | 111-160 aa |
| Specificity: | Dok-6 Polyclonal Antibody detects endogenous levels of Dok-6 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DOK6 at the amino acid range 111-160 |
| Post Translational Modifications | On Ret activation, phosphorylated on one or more C-terminal tyrosine residues by an Src family kinase. |
| Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance. |
| Protein Name | Docking Protein 6Downstream Of Tyrosine Kinase 6 |
| Database Links | Reactome: R-HSA-8853659 |
| Alternative Antibody Names | Anti-Docking Protein 6 antibodyAnti-Downstream Of Tyrosine Kinase 6 antibodyAnti-DOK6 antibodyAnti-DOK5L antibody |
Information sourced from Uniprot.org