Anti-DOK5 antibody (101-150 aa) (STJ92764)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human DOK5 at the amino acid range 101-150
General Information
| Short Description | Rabbit polyclonal anti-Docking protein 5 (101-150 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DOK5 |
| Gene ID | 55816 |
| Uniprot ID | DOK5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human DOK5 at the amino acid range 101-150 |
| Immunogen Region | 101-150 aa |
| Specificity | Dok-5 Polyclonal Antibody detects endogenous levels of Dok-5 protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosine residues in response to insulin, IGF1 and GDNF. |
| Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. |
| Protein Name | Docking Protein 5Downstream Of Tyrosine Kinase 5Insulin Receptor Substrate 6Irs-6Irs6 |
| Database Links | Reactome: R-HSA-8853659 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Docking Protein 5 antibodyAnti-Downstream Of Tyrosine Kinase 5 antibodyAnti-Insulin Receptor Substrate 6 antibodyAnti-Irs-6 antibodyAnti-Irs6 antibodyAnti-DOK5 antibodyAnti-C20orf180 antibody |
Information sourced from Uniprot.org