| Host: | Rabbit |
| Applications: | IHC/IF |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Dynein axonemal heavy chain 2 (329-379 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC-P 1:50-200IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DNAH2 |
| Gene ID: | 146754 |
| Uniprot ID: | DYH2_HUMAN |
| Immunogen Region: | 329-379 aa |
| Specificity: | This antibody detects endogenous levels of DYH2 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human DYH2 at the amino acid range 329-379 |
| Function | As part of the axonemal inner dynein arm complex plays a central role in ciliary beat. Expressed in sperm flagellum, it is required for sperm motility. Dyneins are microtubule-based molecular motors possessing ATPase activities that can convert the chemical energy of ATP into relative sliding between adjacent microtubule doublets to generate ciliary bending. |
| Protein Name | Dynein Axonemal Heavy Chain 2Axonemal Beta Dynein Heavy Chain 2Ciliary Dynein Heavy Chain 2Dynein Heavy Chain Domain-Containing Protein 3 |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeFlagellum Axoneme |
| Alternative Antibody Names | Anti-Dynein Axonemal Heavy Chain 2 antibodyAnti-Axonemal Beta Dynein Heavy Chain 2 antibodyAnti-Ciliary Dynein Heavy Chain 2 antibodyAnti-Dynein Heavy Chain Domain-Containing Protein 3 antibodyAnti-DNAH2 antibodyAnti-DNAHC2 antibodyAnti-DNHD3 antibodyAnti-KIAA1503 antibody |
Information sourced from Uniprot.org