| Short Description : | Mouse monoclonal anti-DNA-RNA Hybrid [S9.6] for use in ICC, IF, IP and ChIP in All samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ICC/IF/IP/ChIP |
| Host: | Mouse |
| Reactivity: | All |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Isotype: | IgG2a |
| Conjugation: | Unconjugated |
| Concentration: | 1mg/mL |
| Purification: | Affinity Purified |
| Dilution Range: | IF 1:50-1:200IP 1:50-1:300ChIP 1:20 |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA, pH 7.3. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Immunogen: | Phi X174 bacteriophage-derived synthetic DNA/RNA |
| Background | The DNA-RNA hybrids are a natural occurrence within eukaryotic cells and their level are high at sites of high transcriptional activity.They are non-canonical nucleic acid structures with transcriptional regulatory functions. Their presence is reported to predispose a locus to chromosomal breakage. The S9.6 monoclonal antibody recognizes DNA-RNA hybrids (also known as R-loops) and does not bind to single or double stranded DNA. |
Information sourced from Uniprot.org
