![Anti-DLL4 nanobody [SAA1284] (STJN000304)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200917/413099/STJN000304-SDS-PAGE-1__77351.1749232600.jpg?c=1 "Anti-DLL4 nanobody [SAA1284] (STJN000304)")
![Anti-DLL4 nanobody [SAA1284] (STJN000304)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200917/413099/STJN000304-SDS-PAGE-1__77351.1749232600.jpg?c=1 "Anti-DLL4 nanobody [SAA1284] (STJN000304)")
Anti-DLL4 nanobody [SAA1284] (STJN000304)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Delta-Like Protein 4 is suitable for use in ELISA research applications. |
| Applications | ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1284 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | DLL4 |
| Gene ID | 54567 |
| Uniprot ID | DLL4_HUMAN |
Additional Info
| Function | Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis.negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate. |
| Protein Name | Delta-Like Protein 4Drosophila Delta Homolog 4Delta4 |
| Database Links | Reactome: R-HSA-2122948Reactome: R-HSA-2644606Reactome: R-HSA-2660826Reactome: R-HSA-2691232Reactome: R-HSA-2894862Reactome: R-HSA-2979096Reactome: R-HSA-9013507Reactome: R-HSA-9013700 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Nanobody Names | Anti-Delta-Like Protein 4 nanobodyAnti-Drosophila Delta Homolog 4 nanobodyAnti-Delta4 nanobodyAnti-DLL4 nanobodyAnti-UNQ1895 nanobodyAnti-PRO4341 nanobody |
Information sourced from Uniprot.org