| Host: |
Human |
| Applications: |
FC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Human monoclonal antibody anti-Delta-Like Protein 4 is suitable for use in Flow Cytometry research applications. |
| Clonality : |
Monoclonal |
| Clone ID : |
SAA0166 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1k |
| Formulation: |
0.01M PBS, pH 7.4. |
| Purification: |
Protein A/G purified from cell culture supernatant. |
| Concentration: |
1 mg/ml |
| Storage Instruction: |
Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Function | Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis.negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate. |
| Protein Name | Delta-Like Protein 4Drosophila Delta Homolog 4Delta4 |
| Database Links | Reactome: R-HSA-2122948Reactome: R-HSA-2644606Reactome: R-HSA-2660826Reactome: R-HSA-2691232Reactome: R-HSA-2894862Reactome: R-HSA-2979096Reactome: R-HSA-9013507Reactome: R-HSA-9013700 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Delta-Like Protein 4 antibodyAnti-Drosophila Delta Homolog 4 antibodyAnti-Delta4 antibodyAnti-DLL4 antibodyAnti-UNQ1895 antibodyAnti-PRO4341 antibody |
Information sourced from Uniprot.org
