| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DLL3 |
| Gene ID: | 10683 |
| Uniprot ID: | DLL3_HUMAN |
| Immunogen Region: | 520-618 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-618 of human DLL3 (NP_058637.1). |
| Immunogen Sequence: | HSQDAGSRLLAGTPEPSVHA LPDALNNLRTQEGSGDGPSS SVDWNRPEDVDPQGIYVISA PSIYAREVATPLFPPLHTGR AGQRQHLLFPYPSSILSVK |
| Post Translational Modifications | Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. |
| Function | Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. |
| Protein Name | Delta-Like Protein 3Drosophila Delta Homolog 3Delta3 |
| Database Links | Reactome: R-HSA-9793380Reactome: R-HSA-9824272 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Delta-Like Protein 3 antibodyAnti-Drosophila Delta Homolog 3 antibodyAnti-Delta3 antibodyAnti-DLL3 antibody |
Information sourced from Uniprot.org