| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Delta-Like Protein 3 (520-618) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:100-1:500 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DLL3 |
| Gene ID: |
10683 |
| Uniprot ID: |
DLL3_HUMAN |
| Immunogen Region: |
520-618 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 520-618 of human DLL3 (NP_058637.1). |
| Immunogen Sequence: |
HSQDAGSRLLAGTPEPSVHA LPDALNNLRTQEGSGDGPSS SVDWNRPEDVDPQGIYVISA PSIYAREVATPLFPPLHTGR AGQRQHLLFPYPSSILSVK |
| Post Translational Modifications | Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. |
| Function | Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. |
| Protein Name | Delta-Like Protein 3Drosophila Delta Homolog 3Delta3 |
| Database Links | Reactome: R-HSA-9793380Reactome: R-HSA-9824272 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Delta-Like Protein 3 antibodyAnti-Drosophila Delta Homolog 3 antibodyAnti-Delta3 antibodyAnti-DLL3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
