| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DLK1 |
| Gene ID: | 8788 |
| Uniprot ID: | DLK1_HUMAN |
| Immunogen Region: | 24-303 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-303 of human DLK1 (P80370). |
| Immunogen Sequence: | AECFPACNPQNGFCEDDNVC RCQPGWQGPLCDQCVTSPGC LHGLCGEPGQCICTDGWDGE LCDRDVRACSSAPCANNRTC VSLDDGLYECSCAPGYSGKD CQKKDGPCVINGSPCQHGGT CVDDEGRASHASCLCPPGFS GNFCEIVANSCTPNPCENDG VCTDIGGDFRCRCPAGFIDK TCSRPVTNCASSPCQNGGTC LQHTQVSYECLCKPEFTGLT CVKKRALSPQQVTRLPSGY |
| Tissue Specificity | Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue. |
| Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. |
| Function | May have a role in neuroendocrine differentiation. |
| Protein Name | Protein Delta Homolog 1Dlk-1Pg2 Cleaved Into - Fetal Antigen 1Fa1 |
| Database Links | Reactome: R-HSA-2122948 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Protein Delta Homolog 1 antibodyAnti-Dlk-1 antibodyAnti-Pg2 Cleaved Into - Fetal Antigen 1 antibodyAnti-Fa1 antibodyAnti-DLK1 antibodyAnti-DLK antibody |
Information sourced from Uniprot.org