| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Disks large-associated protein 5 (791-840 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:40000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DLGAP5 |
| Gene ID: | 9787 |
| Uniprot ID: | DLGP5_HUMAN |
| Immunogen Region: | 791-840 aa |
| Specificity: | HURP Polyclonal Antibody detects endogenous levels of HURP protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DLGAP5 at the amino acid range 791-840 |
| Post Translational Modifications | Ubiquitinated, leading to its degradation. Decreased phosphorylation levels are associated with the differentiation of intestinal epithelial cells. |
| Function | Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells. |
| Protein Name | Disks Large-Associated Protein 5 Dap-5 Discs Large Homolog 7 Disks Large-Associated Protein Dlg7 Hepatoma Up-Regulated Protein Hurp |
| Database Links | Reactome: R-HSA-9013508 |
| Cellular Localisation | Nucleus Cytoplasm Cytoskeleton Spindle Localizes To The Spindle In Mitotic Cells Colocalizes With Cdh1 At Sites Of Cell-Cell Contact In Intestinal Epithelial Cells |
| Alternative Antibody Names | Anti-Disks Large-Associated Protein 5 antibody Anti-Dap-5 antibody Anti-Discs Large Homolog 7 antibody Anti-Disks Large-Associated Protein Dlg7 antibody Anti-Hepatoma Up-Regulated Protein antibody Anti-Hurp antibody Anti-DLGAP5 antibody Anti-DLG7 antibody Anti-KIAA0008 antibody |
Information sourced from Uniprot.org