| Host: | Rabbit |
| Applications: | WB/ICC/IF/FC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Dishevelled 3 for use in WB, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Purification: | Affinity Purified |
| Dilution Range: | WB-1:500-1:1000ICC/IF-1:20-1:50FC-1:100-1:200 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | DVL3 |
| Gene ID: | 1857 |
| Uniprot ID: | DVL3_HUMAN |
| Immunogen: | Peptide |
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains. Phosphorylated by CSNK1D. Arginine methylation may function as a switch in regulation of function in Wnt signaling. |
| Function | Involved in the signal transduction pathway mediated by multiple Wnt genes. |
| Protein Name | Segment Polarity Protein Dishevelled Homolog Dvl-3Dishevelled-3Dsh Homolog 3 |
| Database Links | Reactome: R-HSA-201681Reactome: R-HSA-201688Reactome: R-HSA-4086400Reactome: R-HSA-4641258Reactome: R-HSA-4641262Reactome: R-HSA-5368598Reactome: R-HSA-5663220Reactome: R-HSA-9673324 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Segment Polarity Protein Dishevelled Homolog Dvl-3 antibodyAnti-Dishevelled-3 antibodyAnti-Dsh Homolog 3 antibodyAnti-DVL3 antibodyAnti-KIAA0208 antibody |
Information sourced from Uniprot.org
