| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Death-inducer obliterator 1 (161-210 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DIDO1 |
| Gene ID: | 11083 |
| Uniprot ID: | DIDO1_HUMAN |
| Immunogen Region: | 161-210 aa |
| Specificity: | Dio-1 Polyclonal Antibody detects endogenous levels of Dio-1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DIDO1 at the amino acid range 161-210 |
| Function | Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Required for early embryonic stem cell development. Isoform 2: Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes. |
| Protein Name | Death-Inducer Obliterator 1Dio-1Hdido1Death-Associated Transcription Factor 1Datf-1 |
| Database Links | Reactome: R-HSA-1221632 Q9BTC0-1 |
| Cellular Localisation | CytoplasmNucleusCytoskeletonSpindleTranslocates To The Nucleus After Pro-Apoptotic StimuliTranslocates To The Mitotic Spindle Upon Loss Of Interaction With H3k4me3 During Early Mitosis |
| Alternative Antibody Names | Anti-Death-Inducer Obliterator 1 antibodyAnti-Dio-1 antibodyAnti-Hdido1 antibodyAnti-Death-Associated Transcription Factor 1 antibodyAnti-Datf-1 antibodyAnti-DIDO1 antibodyAnti-C20orf158 antibodyAnti-DATF1 antibodyAnti-KIAA0333 antibody |
Information sourced from Uniprot.org