| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DHX8 |
| Gene ID: | 1659 |
| Uniprot ID: | DHX8_HUMAN |
| Immunogen Region: | 1001-1220 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1001-1220 of human DHX8 (NP_004932.1). |
| Immunogen Sequence: | CSEEMLTIVSMLSVQNVFYR PKDKQALADQKKAKFHQTEG DHLTLLAVYNSWKNNKFSNP WCYENFIQARSLRRAQDIRK QMLGIMDRHKLDVVSCGKST VRVQKAICSGFFRNAAKKDP QEGYRTLIDQQVVYIHPSSA LFNRQPEWVVYHELVLTTKE YMREVTTIDPRWLVEFAPAF FKVSDPTKLSKQKKQQRLEP LYNRYEEPNAWRISRAFRRR |
| Tissue Specificity | Expressed in skin, cervix and nerve. Also expressed in the brain. |
| Function | Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. |
| Protein Name | Atp-Dependent Rna Helicase Dhx8Deah Box Protein 8Rna Helicase Hrh1 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Atp-Dependent Rna Helicase Dhx8 antibodyAnti-Deah Box Protein 8 antibodyAnti-Rna Helicase Hrh1 antibodyAnti-DHX8 antibodyAnti-DDX8 antibody |
Information sourced from Uniprot.org