Anti-DHRS9 antibody (18-319) (STJ28246)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal DHRS9 (18-319) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:10-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | DHRS9 |
| Gene ID | 10170 |
| Uniprot ID | DHRS9_HUMAN |
| Immunogen Region | 18-319 |
| Immunogen Sequence | RKGKLKIEDITDKYIFITGC DSGFGNLAARTFDKKGFHVI AACLTESGSTALKAETSERL RTVLLDVTDPENVKRTAQWV KNQVGEKGLWGLINNAGVPG VLAPTDWLTLEDYREPIEVN LFGLISVTLNMLPLVKKAQG RVINVSSVGGRLAIVGGGYT PSKYAVEGFNDSLRRDMKAF GVHVSCIEPGLFKTNLADPV KVIEKKLAIWEQLSPDIKQQ YGEGYIEKSLDKLKGNKSY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 18-319 of human DHRS9 (NP_001135743.1). |
Additional Info
| Tissue Specificity | Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node. |
| Function | 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone. Also plays a role in the biosynthesis of retinoic acid from retinaldehyde. Can utilize both NADH and NADPH. |
| Protein Name | Dehydrogenase/Reductase Sdr Family Member 93-Alpha Hydroxysteroid Dehydrogenase3-Alpha-HsdNadp-Dependent Retinol Dehydrogenase/ReductaseRdh-E2RdhlRetinol Dehydrogenase 15Short Chain Dehydrogenase/Reductase Family 9c Member 4Short-Chain Dehydrogenase/Reductase Retsdr8Tracheobronchial Epithelial Cell-Specific Retinol DehydrogenaseRdh-Tbe |
| Database Links | Reactome: R-HSA-2453902Reactome: R-HSA-5365859 |
| Cellular Localisation | Microsome MembraneEndoplasmic Reticulum MembraneAssociated With Microsomal Membranes |
| Alternative Antibody Names | Anti-Dehydrogenase/Reductase Sdr Family Member 9 antibodyAnti-3-Alpha Hydroxysteroid Dehydrogenase antibodyAnti-3-Alpha-Hsd antibodyAnti-Nadp-Dependent Retinol Dehydrogenase/Reductase antibodyAnti-Rdh-E2 antibodyAnti-Rdhl antibodyAnti-Retinol Dehydrogenase 15 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 9c Member 4 antibodyAnti-Short-Chain Dehydrogenase/Reductase Retsdr8 antibodyAnti-Tracheobronchial Epithelial Cell-Specific Retinol Dehydrogenase antibodyAnti-Rdh-Tbe antibodyAnti-DHRS9 antibodyAnti-RDH15 antibodyAnti-SDR9C4 antibodyAnti-UNQ835 antibodyAnti-PRO1773 antibody |
Information sourced from Uniprot.org