| Host: | Rabbit |
| Applications: | IHC/IF/WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Dehydrogenase/reductase SDR family member 11 (111-160 aa) is suitable for use in Immunohistochemistry, Immunofluorescence, Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DHRS11 |
| Gene ID: | 79154 |
| Uniprot ID: | DHR11_HUMAN |
| Immunogen Region: | 111-160 aa |
| Specificity: | DHRS11 Polyclonal Antibody detects endogenous levels of DHRS11 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DHRS11 at the amino acid range 111-160 |
| Function | Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones. |
| Protein Name | Dehydrogenase/Reductase Sdr Family Member 1117-Beta-Hydroxysteroid Dehydrogenase3-Beta-Hydroxysteroid 3-DehydrogenaseEstradiol 17-Beta-DehydrogenaseShort-Chain Dehydrogenase/Reductase Family 24c Member 1 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Dehydrogenase/Reductase Sdr Family Member 11 antibodyAnti-17-Beta-Hydroxysteroid Dehydrogenase antibodyAnti-3-Beta-Hydroxysteroid 3-Dehydrogenase antibodyAnti-Estradiol 17-Beta-Dehydrogenase antibodyAnti-Short-Chain Dehydrogenase/Reductase Family 24c Member 1 antibodyAnti-DHRS11 antibodyAnti-SDR24C1 antibodyAnti-UNQ836 antibodyAnti-PRO1774 antibody |
Information sourced from Uniprot.org