Host: |
Rabbit |
Applications: |
IHC/IF/WB/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Dehydrogenase/reductase SDR family member 11 (111-160 aa) is suitable for use in Immunohistochemistry, Immunofluorescence, Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DHRS11 |
Gene ID: |
79154 |
Uniprot ID: |
DHR11_HUMAN |
Immunogen Region: |
111-160 aa |
Specificity: |
DHRS11 Polyclonal Antibody detects endogenous levels of DHRS11 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human DHRS11 at the amino acid range 111-160 |
Function | Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones. |
Protein Name | Dehydrogenase/Reductase Sdr Family Member 1117-Beta-Hydroxysteroid Dehydrogenase3-Beta-Hydroxysteroid 3-DehydrogenaseEstradiol 17-Beta-DehydrogenaseShort-Chain Dehydrogenase/Reductase Family 24c Member 1 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Dehydrogenase/Reductase Sdr Family Member 11 antibodyAnti-17-Beta-Hydroxysteroid Dehydrogenase antibodyAnti-3-Beta-Hydroxysteroid 3-Dehydrogenase antibodyAnti-Estradiol 17-Beta-Dehydrogenase antibodyAnti-Short-Chain Dehydrogenase/Reductase Family 24c Member 1 antibodyAnti-DHRS11 antibodyAnti-SDR24C1 antibodyAnti-UNQ836 antibodyAnti-PRO1774 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance