Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Diacylglycerol O-acyltransferase 2 (1-50 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DGAT2 |
Gene ID: |
84649 |
Uniprot ID: |
DGAT2_HUMAN |
Immunogen Region: |
1-50 aa |
Specificity: |
DGAT2 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from part of the human protein at the amino acid range 1-50 |
Function | Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides. Functions also as an acyl-CoA retinol acyltransferase (ARAT). Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG). |
Protein Name | Diacylglycerol O-Acyltransferase 2Acyl-Coa Retinol O-Fatty-AcyltransferaseAratRetinol O-Fatty-AcyltransferaseDiglyceride Acyltransferase 2 |
Database Links | Reactome: R-HSA-1482883Reactome: R-HSA-75109 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinLipid DropletCytoplasmPerinuclear Region |
Alternative Antibody Names | Anti-Diacylglycerol O-Acyltransferase 2 antibodyAnti-Acyl-Coa Retinol O-Fatty-Acyltransferase antibodyAnti-Arat antibodyAnti-Retinol O-Fatty-Acyltransferase antibodyAnti-Diglyceride Acyltransferase 2 antibodyAnti-DGAT2 antibodyAnti-HMFN1045 antibodyAnti-UNQ738 antibodyAnti-PRO1433 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance