| Host: | Rabbit |
| Applications: | IHC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein Dennd6a is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: | Antigen affinity purification |
| Concentration: | 1.08 mg/mL |
| Dilution Range: | IHC 1:100-1:200 |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Gene Symbol: | DENND6A |
| Gene ID: | 201627 |
| Uniprot ID: | DEN6A_HUMAN |
| Immunogen: | Fusion protein of human DENND6A |
| Function | Guanine nucleotide exchange factor (GEF) for RAB14. Component of an endocytic recycling pathway that is required for the control of ADAM10 transport, shedding of N-cadherin/CDH2 by ADAM9 or ADAM10 and regulation of cell-cell junctions. Required for RAB14 recruitment to recycling endosomes. |
| Protein Name | Protein Dennd6aDenn Domain-Containing Protein 6a |
| Database Links | Reactome: R-HSA-8876198 |
| Cellular Localisation | Recycling EndosomeCytoplasm |
| Alternative Antibody Names | Anti-Protein Dennd6a antibodyAnti-Denn Domain-Containing Protein 6a antibodyAnti-DENND6A antibodyAnti-FAM116A antibody |
Information sourced from Uniprot.org