| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DDX25 (284-483) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DDX25 |
| Gene ID: |
29118 |
| Uniprot ID: |
DDX25_HUMAN |
| Immunogen Region: |
284-483 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 284-483 of human DDX25 (NP_037396.3). |
| Immunogen Sequence: |
DSVWHFAERIIPDPNVIKLR KEELTLNNIRQYYVLCEHRK DKYQALCNIYGSITIGQAII FCQTRRNAKWLTVEMIQDGH QVSLLSGELTVEQRASIIQR FRDGKEKVLITTNVCARGID VKQVTIVVNFDLPVKQGEEP DYETYLHRIGRTGRFGKKGL AFNMIEVDELPSLMKIQDHF NSSIKQLNAEDMDEIEKIDY |
| Tissue Specificity | Highly expressed in the Leydig and germ cells of the testis and weakly expressed in the pituitary and hypothalamus. |
| Post Translational Modifications | Phosphorylated on threonine residues. The phosphorylated form is found in the cytoplasm but not in the nucleus. |
| Function | ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development. |
| Protein Name | Atp-Dependent Rna Helicase Ddx25Dead Box Protein 25Gonadotropin-Regulated Testicular Rna Helicase |
| Cellular Localisation | CytoplasmNucleusDetected In Both Cytoplasm And Nucleus Of Testicular CellsAlso Detected In Chromatoid Bodies Of Round Spermatids |
| Alternative Antibody Names | Anti-Atp-Dependent Rna Helicase Ddx25 antibodyAnti-Dead Box Protein 25 antibodyAnti-Gonadotropin-Regulated Testicular Rna Helicase antibodyAnti-DDX25 antibodyAnti-GRTH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
