| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DCTN6 (1-190) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DCTN6 |
| Gene ID: |
10671 |
| Uniprot ID: |
DCTN6_HUMAN |
| Immunogen Region: |
1-190 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human DCTN6 (NP_006562.1). |
| Immunogen Sequence: |
MAEKTQKSVKIAPGAVVCVE SEIRGDVTIGPRTVIHPKAR IIAEAGPIVIGEGNLIEEQA LIINAYPDNITPDTEDPEPK PMIIGTNNVFEVGCYSQAMK MGDNNVIESKAYVGRNVILT SGCIIGACCNLNTFEVIPEN TVIYGADCLRRVQTERPQPQ TLQLDFLMKILPNYHHLKKT MKGSSTPVKN |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylation at Thr-186 by CDK1 during mitotic prometaphase creates a binding site for PLK1 that facilitates its recruitment to kinetochores. |
| Function | Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. |
| Protein Name | Dynactin Subunit 6Dynactin Subunit P27Protein Ws-3 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-3371497Reactome: R-HSA-6807878Reactome: R-HSA-6811436 |
| Cellular Localisation | CytoplasmCytoskeletonChromosomeCentromereKinetochore |
| Alternative Antibody Names | Anti-Dynactin Subunit 6 antibodyAnti-Dynactin Subunit P27 antibodyAnti-Protein Ws-3 antibodyAnti-DCTN6 antibodyAnti-WS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and ATF2 knockout (KO) 293T cells, using [KO Validated] ATF2 Rabbit polyclonal antibody (STJ22702) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/99177/383848/STJ22702_1__38112.1713152438.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and ATF2 knockout (KO) 293T cells, using [KO Validated] ATF2 Rabbit polyclonal antibody (STJ22702) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")