• Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-DCTN3 antibody (117-167 aa) (STJ194154)

SKU:
STJ194154

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dynactin subunit 3 (117-167 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DCTN3
Gene ID: 11258
Uniprot ID: DCTN3_HUMAN
Immunogen Region: 117-167 aa
Specificity: This antibody detects endogenous levels of DCTN3 at Human/Mouse
Immunogen: Synthesized peptide derived from the human DCTN3 at the amino acid range 117-167
Function Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. Together with dynein may be involved in spindle assembly and cytokinesis.
Protein Name Dynactin Subunit 3
Dynactin Complex Subunit 22 Kda Subunit
P22
Database Links Reactome: R-HSA-2132295
Reactome: R-HSA-2565942
Reactome: R-HSA-3371497
Reactome: R-HSA-380259
Reactome: R-HSA-380270
Reactome: R-HSA-380284
Reactome: R-HSA-380320
Reactome: R-HSA-5620912
Reactome: R-HSA-6807878
Reactome: R-HSA-6811436
Reactome: R-HSA-8854518
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Chromosome
Centromere
Kinetochore
Spindle
Cleavage Furrow
Midbody
Localizes To Punctate Cytoplasmic Structures And To The Centrosome During Interphase
And To Kinetochores And To Spindle Poles Throughout Mitosis
Colocalizes With Dynein To The Cleavage Furrow And To Midbody Of Dividing Cells
Alternative Antibody Names Anti-Dynactin Subunit 3 antibody
Anti-Dynactin Complex Subunit 22 Kda Subunit antibody
Anti-P22 antibody
Anti-DCTN3 antibody
Anti-DCTN22 antibody

Information sourced from Uniprot.org

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