| Short Description : | Rabbit polyclonal anti-L-dopachrome tautomerase (51-100 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DCT |
| Gene ID: | 1638 |
| Uniprot ID: | TYRP2_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DCT at the amino acid range 51-100 |
| Immunogen Region: | 51-100 aa |
| Specificity: | TRP2 Polyclonal Antibody detects endogenous levels of TRP2 protein. |
| Function | Plays a role in melanin biosynthesis. Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). |
| Protein Name | L-Dopachrome TautomeraseDctDtL-Dopachrome Delta-IsomeraseTyrosinase-Related Protein 2Trp-2Trp2 |
| Database Links | Reactome: R-HSA-5662702Reactome: R-HSA-9824585 |
| Cellular Localisation | Melanosome MembraneSingle-Pass Type I Membrane ProteinMelanosomeProper Trafficking To Melanosome Is Regulated By Sgsm2Ankrd27Rab9aRab32 And Rab38 |
| Alternative Antibody Names | Anti-L-Dopachrome Tautomerase antibodyAnti-Dct antibodyAnti-Dt antibodyAnti-L-Dopachrome Delta-Isomerase antibodyAnti-Tyrosinase-Related Protein 2 antibodyAnti-Trp-2 antibodyAnti-Trp2 antibodyAnti-DCT antibodyAnti-TYRP2 antibody |
Information sourced from Uniprot.org
