Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-L-dopachrome tautomerase (51-100 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:40000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DCT |
Gene ID: |
1638 |
Uniprot ID: |
TYRP2_HUMAN |
Immunogen Region: |
51-100 aa |
Specificity: |
TRP2 Polyclonal Antibody detects endogenous levels of TRP2 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human DCT at the amino acid range 51-100 |
Function | Plays a role in melanin biosynthesis. Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). |
Protein Name | L-Dopachrome TautomeraseDctDtL-Dopachrome Delta-IsomeraseTyrosinase-Related Protein 2Trp-2Trp2 |
Database Links | Reactome: R-HSA-5662702 |
Cellular Localisation | Melanosome MembraneSingle-Pass Type I Membrane ProteinMelanosomeProper Trafficking To Melanosome Is Regulated By Sgsm2Ankrd27Rab9aRab32 And Rab38 |
Alternative Antibody Names | Anti-L-Dopachrome Tautomerase antibodyAnti-Dct antibodyAnti-Dt antibodyAnti-L-Dopachrome Delta-Isomerase antibodyAnti-Tyrosinase-Related Protein 2 antibodyAnti-Trp-2 antibodyAnti-Trp2 antibodyAnti-DCT antibodyAnti-TYRP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance