| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-DCR2 (287-386) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S6MR |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TNFRSF10D |
| Gene ID: |
8793 |
| Uniprot ID: |
TR10D_HUMAN |
| Immunogen Region: |
287-386 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 287-386 of human DCR2 (Q9UBN6). |
| Immunogen Sequence: |
PTQVSEQEIQGQELAELTGV TVELPEEPQRLLEQAEAEGC QRRRLLVPVNDADSADISTL LDASATLEEGHAKETIQDQL VGSEKLFYEEDEAGSATSCL |
| Tissue Specificity | Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart. |
| Function | Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. it cannot but it can induce the NF-kappa-B pathway. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 10dDecoy Receptor 2Dcr2Tnf-Related Apoptosis-Inducing Ligand Receptor 4Trail Receptor 4Trail-R4Trail Receptor With A Truncated Death DomainCd Antigen Cd264 |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-6803211Reactome: R-HSA-75158 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 10d antibodyAnti-Decoy Receptor 2 antibodyAnti-Dcr2 antibodyAnti-Tnf-Related Apoptosis-Inducing Ligand Receptor 4 antibodyAnti-Trail Receptor 4 antibodyAnti-Trail-R4 antibodyAnti-Trail Receptor With A Truncated Death Domain antibodyAnti-Cd Antigen Cd264 antibodyAnti-TNFRSF10D antibodyAnti-DCR2 antibodyAnti-TRAILR4 antibodyAnti-TRUNDD antibodyAnti-UNQ251 antibodyAnti-PRO288 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
