| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Serine/threonine-protein kinase DCLK2 (1-50 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DCLK2 |
| Gene ID: | 166614 |
| Uniprot ID: | DCLK2_HUMAN |
| Immunogen Region: | 1-50 aa |
| Specificity: | DCAMKL2 Polyclonal Antibody detects endogenous levels of DCAMKL2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human DCLK2 at the amino acid range 1-50 |
| Post Translational Modifications | Autophosphorylated. |
| Function | Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm. |
| Protein Name | Serine/Threonine-Protein Kinase Dclk2Camk-Like Creb Regulatory Kinase 2Cl2Click-IiClick2Doublecortin Domain-Containing Protein 3bDoublecortin-Like And Cam Kinase-Like 2Doublecortin-Like Kinase 2 |
| Cellular Localisation | CytoplasmCytoskeletonColocalizes With Microtubules |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Kinase Dclk2 antibodyAnti-Camk-Like Creb Regulatory Kinase 2 antibodyAnti-Cl2 antibodyAnti-Click-Ii antibodyAnti-Click2 antibodyAnti-Doublecortin Domain-Containing Protein 3b antibodyAnti-Doublecortin-Like And Cam Kinase-Like 2 antibodyAnti-Doublecortin-Like Kinase 2 antibodyAnti-DCLK2 antibodyAnti-DCAMKL2 antibodyAnti-DCDC3B antibodyAnti-DCK2 antibody |
Information sourced from Uniprot.org