| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Deleted in azoospermia-like (202-252 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DAZL |
| Gene ID: | 1618 |
| Uniprot ID: | DAZL_HUMAN |
| Immunogen Region: | 202-252 aa |
| Specificity: | This antibody detects endogenous levels of DAZL at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human DAZL at the amino acid range 202-252 |
| Function | RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. |
| Protein Name | Deleted In Azoospermia-LikeDaz HomologDaz-Like AutosomalDeleted In Azoospermia-Like 1Spgy-Like-Autosomal |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicNuclear In Spermatogonia Until Near The End Of The Meiotic Prophase And Cytoplasmic Localization From Then Onward |
| Alternative Antibody Names | Anti-Deleted In Azoospermia-Like antibodyAnti-Daz Homolog antibodyAnti-Daz-Like Autosomal antibodyAnti-Deleted In Azoospermia-Like 1 antibodyAnti-Spgy-Like-Autosomal antibodyAnti-DAZL antibodyAnti-DAZH antibodyAnti-DAZL1 antibodyAnti-DAZLA antibodyAnti-SPGYLA antibody |
Information sourced from Uniprot.org