| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DAZL (186-295) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DAZL |
| Gene ID: |
1618 |
| Uniprot ID: |
DAZL_HUMAN |
| Immunogen Region: |
186-295 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 186-295 of human DAZL (NP_001342.2). |
| Immunogen Sequence: |
VYNYQMPPQWPVGEQRSYVV PPAYSAVNYHCNEVDPGAEV VPNECSVHEATPPSGNGPQK KSVDRSIQTVVSCLFNPENR LRNSVVTQDDYFKDKRVHHF RRSRAMLKSV |
| Tissue Specificity | Testis specific. |
| Function | RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. |
| Protein Name | Deleted In Azoospermia-LikeDaz HomologDaz-Like AutosomalDeleted In Azoospermia-Like 1Spgy-Like-Autosomal |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicNuclear In Spermatogonia Until Near The End Of The Meiotic Prophase And Cytoplasmic Localization From Then Onward |
| Alternative Antibody Names | Anti-Deleted In Azoospermia-Like antibodyAnti-Daz Homolog antibodyAnti-Daz-Like Autosomal antibodyAnti-Deleted In Azoospermia-Like 1 antibodyAnti-Spgy-Like-Autosomal antibodyAnti-DAZL antibodyAnti-DAZH antibodyAnti-DAZL1 antibodyAnti-DAZLA antibodyAnti-SPGYLA antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
