![Anti-Cytomegalovirus antibody [8B1.2, 1G5.2&2D4.2] (STJ16100451)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149168/346794/STJ16100451_1__60961.1681998896.jpg?c=1 "Anti-Cytomegalovirus antibody [8B1.2, 1G5.2&2D4.2] (STJ16100451)")
![Anti-Cytomegalovirus antibody [8B1.2, 1G5.2&2D4.2] (STJ16100451)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149168/346794/STJ16100451_1__60961.1681998896.jpg?c=1 "Anti-Cytomegalovirus antibody [8B1.2, 1G5.2&2D4.2] (STJ16100451)")
Anti-Cytomegalovirus antibody [8B1.2, 1G5.2&2D4.2] (STJ16100451)
SPECIFICATIONS
ClonalityMix
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse mix anti-Cytomegalovirus for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Mix |
| Clone ID | 8B1.2, 1G5.2&2D4.2 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Dilution Range | IHC 1:25 – 1:50 |
| Formulation | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
Additional Info
| Background | Human cytomegalovirus (CMV) is a Beta-herpesvirus (human herpesvirus 5) that causes widespread persistent infection. CMV continues to be an important opportunistic pathogen in immunocompromised patients. It is estimated that 30% of transplant recipients experience CMV disease. The range of organ involvement in post-transplant CMV disease is wide; hepatitis occurs in 40% of liver transplant recipients, and pneumonitis is more frequently seen in heart and heart-lung transplant patients. Other organs that are commonly affected are the gastrointestinal tract and the peripheral and central nervous systems. Histologic diagnosis of CMV in fixed tissues usually rests on identifying characteristic cytopathic effects including intranuclear inclusions, cytoplasmic inclusions, or both, especially in the endothelial cells. However, histologic examination lacks sensitivity, and in some cases atypical cytopathic features can be confused with reactive or degenerative changes. |
Information sourced from Uniprot.org