| Host: | Mouse |
| Applications: | WB/IHC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Keratin, type II cytoskeletal 6A and Keratin, type II cytoskeletal 6B and Keratin, type II cytoskeletal 6C is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 4A1 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Purification: | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range: | WB 1:1000IF 1:200IHC 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KRT6BKRT6C38542868873853K2C6B_HUMANK2C6C_HUMANK2C6A_HUMAN |
| Specificity: | The antibody detects endogenous Cytokeratin 6 proteins. |
| Immunogen: | Synthetic Peptide of Cytokeratin 6 |
| Function | Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. |
| Protein Name | Keratin - Type Ii Cytoskeletal 6aCytokeratin-6aCk-6aCytokeratin-6dCk-6dKeratin-6aK6aType-Ii Keratin Kb6Allergen Hom S 5 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 6a antibodyAnti-Cytokeratin-6a antibodyAnti-Ck-6a antibodyAnti-Cytokeratin-6d antibodyAnti-Ck-6d antibodyAnti-Keratin-6a antibodyAnti-K6a antibodyAnti-Type-Ii Keratin Kb6 antibodyAnti-Allergen Hom S 5 antibodyAnti-KRT6A antibodyAnti-K6A antibodyAnti-KRT6D antibody |
Information sourced from Uniprot.org