Anti-Cytokeratin 6 antibody (1-100) [S1MR] (STJ11103571)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Cytokeratin 6 (KRT6) (1-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S1MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT6A |
| Gene ID | 3853 |
| Uniprot ID | K2C6A_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MASTSTTIRSHSSSRRGFSA NSARLPGVSRSGFSSVSVSR SRGSGGLGGACGGAGFGSRS LYGLGGSKRISIGGGSCAIS GGYGSRAGGSYGFGGAGSGF |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cytokeratin 6 (KRT6) (P02538). |
Additional Info
| Tissue Specificity | Expressed in the corneal epithelium (at protein level). |
| Function | Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. |
| Protein Name | Keratin - Type Ii Cytoskeletal 6aCytokeratin-6aCk-6aCytokeratin-6dCk-6dKeratin-6aK6aType-Ii Keratin Kb6Allergen Hom S 5 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 6a antibodyAnti-Cytokeratin-6a antibodyAnti-Ck-6a antibodyAnti-Cytokeratin-6d antibodyAnti-Ck-6d antibodyAnti-Keratin-6a antibodyAnti-K6a antibodyAnti-Type-Ii Keratin Kb6 antibodyAnti-Allergen Hom S 5 antibodyAnti-KRT6A antibodyAnti-K6A antibodyAnti-KRT6D antibody |
Information sourced from Uniprot.org