Anti-Cytokeratin 16 antibody (1-100) [S9MR] (STJ11103629)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Cytokeratin 16 (KRT16) (1-100) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S9MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:500-1:2000IF/ICC:1:100-1:400ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT16 |
| Gene ID | 3868 |
| Uniprot ID | K1C16_HUMAN |
| Immunogen Region | 1-100 |
| Immunogen Sequence | MTTCSRQFTSSSSMKGSCGI GGGIGGGSSRISSVLAGGSC RAPSTYGGGLSVSSRFSSGG ACGLGGGYGGGFSSSSSFGS GFGGGYGGGLGAGFGGGLGA |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cytokeratin 16 (KRT16) (P08779). |
Additional Info
| Tissue Specificity | Expressed in the corneal epithelium (at protein level). |
| Function | Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. |
| Protein Name | Keratin - Type I Cytoskeletal 16Cytokeratin-16Ck-16Keratin-16K16 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 16 antibodyAnti-Cytokeratin-16 antibodyAnti-Ck-16 antibodyAnti-Keratin-16 antibodyAnti-K16 antibodyAnti-KRT16 antibodyAnti-KRT16A antibody |
Information sourced from Uniprot.org