Western blot analysis of CK14 at dilution of 1:1000

Anti-Cytokeratin 14 antibody [SM5119] (STJA0005119)

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STJA0005119
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Host: Mouse
Applications: WB/IHC/IF
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Cytokeratin 14 is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality : Monoclonal
Clone ID : SM5119
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol.
Purification: Affinity purification
Dilution Range: WB (M) 1:500-1:1000
IHC/IF (H, M, R) 1:500-1:1000
Storage Instruction: Store at-20C for up to one year, and avoid repeated freeze-thaw cycles.
Gene Symbol: Krt14
Gene ID: 16664
Uniprot ID: K1C14_MOUSE
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 14
Post Translational Modifications A disulfide bond is formed between rather than within filaments and promotes the formation of a keratin filament cage around the nucleus. Ubiquitinated by the BCR(KLHL24) E3 ubiquitin ligase complex.
Function The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
Protein Name Keratin - Type I Cytoskeletal 14
Cytokeratin-14
Ck-14
Keratin-14
K14
Database Links Reactome: R-MMU-446107
Reactome: -MMU-6805567
Reactome: -MMU-6809371
Cellular Localisation Cytoplasm
Nucleus
Expressed In Both As A Filamentous Pattern
Alternative Antibody Names Anti-Keratin - Type I Cytoskeletal 14 antibody
Anti-Cytokeratin-14 antibody
Anti-Ck-14 antibody
Anti-Keratin-14 antibody
Anti-K14 antibody
Anti-Krt14 antibody
Anti-Krt1-14 antibody

Information sourced from Uniprot.org

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