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Anti-Cytokeratin 14 antibody [SM5119] (STJA0005119)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG
ImmunogenKLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 14
General Information
| Short Description | Mouse monoclonal anti-Cytokeratin 14 for use in WB, IHC and IF in Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF |
| Host | Mouse |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SM5119 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB (M) 1:500-1:1000IHC/IF (H, M, R) 1:500-1:1000 |
| Formulation | PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | Krt14 |
| Gene ID | 16664 |
| Uniprot ID | K1C14_MOUSE |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 14 |
Additional Info
| Post Translational Modifications | A disulfide bond is formed between rather than within filaments and promotes the formation of a keratin filament cage around the nucleus. Ubiquitinated by the BCR(KLHL24) E3 ubiquitin ligase complex. |
| Function | The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. |
| Protein Name | Keratin - Type I Cytoskeletal 14Cytokeratin-14Ck-14Keratin-14K14 |
| Database Links | Reactome: R-MMU-446107Reactome: -MMU-6805567Reactome: -MMU-6809371 |
| Cellular Localisation | CytoplasmNucleusExpressed In Both As A Filamentous Pattern |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 14 antibodyAnti-Cytokeratin-14 antibodyAnti-Ck-14 antibodyAnti-Keratin-14 antibodyAnti-K14 antibodyAnti-Krt14 antibodyAnti-Krt1-14 antibody |
Information sourced from Uniprot.org