| Function | A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics (Probable). |
| Protein Name | Cytochrome P450 2e14-Nitrophenol 2-HydroxylaseCypiie1Cytochrome P450-J |
| Database Links | Reactome: R-HSA-211981Reactome: R-HSA-211999Reactome: R-HSA-9027307Reactome: R-HSA-9749641Reactome: R-HSA-9753281 |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinMicrosome MembraneMitochondrion Inner MembranePost-Translationally Targeted To MitochondriaTomm70 Is Required For The Translocation Across The Mitochondrial Outer MembraneAfter Translocation Into The MatrixAssociates With The Inner Membrane As A Membrane Extrinsic Protein |
| Alternative Antibody Names | Anti-Cytochrome P450 2e1 antibodyAnti-4-Nitrophenol 2-Hydroxylase antibodyAnti-Cypiie1 antibodyAnti-Cytochrome P450-J antibodyAnti-CYP2E1 antibodyAnti-CYP2E antibody |
Information sourced from Uniprot.org
