Anti-Cystatin C antibody [10002] (STJ400218)

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STJ400218

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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Cystatin C is suitable for use in ELISA research applications.
Clonality: Monoclonal
Clone ID: 10002
Conjugation: Unconjugated
Isotype: IgG2b
Formulation: 50 mM Na-citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
Purification: Greater than 95% purity
Concentration: 5.0 mg/ml (+/-10 %)
Storage Instruction: Unspecified, storage at 2–8°C. Temperature analysis:-70 °C, 21 days Not Determined (N/D)-20 °C, 14 days OK +4 °C, 14 days OK +35 °C, 14 days OK +45 °C, 7 days OK. Shelf life stability testing at 2–8 °C in the product buffer.
Association Rate Constant: 2.1 x 106 1/Ms
Determination Method: SPR analysis (ProteOn XPR36)
Immunoreactivity: 80–120 % compared to the reference sample in an FIA test
Gene Symbol: CST3
Gene ID: 1471
Uniprot ID: CYTC_HUMAN
Immunogen: Human Cystatin C
Tissue Specificity Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
Post Translational Modifications The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.
Function As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
Protein Name Cystatin-C
Cystatin-3
Gamma-Trace
Neuroendocrine Basic Polypeptide
Post-Gamma-Globulin
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-6798695
Reactome: R-HSA-8957275
Reactome: R-HSA-977225
Cellular Localisation Secreted
Alternative Antibody Names Anti-Cystatin-C antibody
Anti-Cystatin-3 antibody
Anti-Gamma-Trace antibody
Anti-Neuroendocrine Basic Polypeptide antibody
Anti-Post-Gamma-Globulin antibody
Anti-CST3 antibody

Information sourced from Uniprot.org

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