| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | CYP3A43 |
| Gene ID: | 64816 |
| Uniprot ID: | CP343_HUMAN |
| Immunogen Region: | 134-393 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 134-393 of human CYP3A43 (NP_001265850.1). |
| Immunogen Sequence: | DVTHFLKNSIERMKESRLKD KQKHRVDFFQQMIDSQNSKE TKSHKALSDLELVAQSIIII FAAYDTTSTTLPFIMYELAT HPDVQQKLQEEIDAVLPNKA PVTYDALVQMEYLDMVVNET LRLFPVVSRVTRVCKKDIEI NGVFIPKGLAVMVPIYALHH DPKYWTEPEKFCPERFSKKN KDSIDLYRYIPFGAGPRNCI GMRFALTNIKLAVIRALQNF SFKPCKETQIPLKLDNLPI |
| Tissue Specificity | Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle. |
| Function | Exhibits low testosterone 6-beta-hydroxylase activity. |
| Protein Name | Cytochrome P450 3a43 |
| Database Links | Reactome: R-HSA-211958Reactome: R-HSA-211981 |
| Cellular Localisation | Endoplasmic Reticulum MembranePeripheral Membrane ProteinMicrosome Membrane |
| Alternative Antibody Names | Anti-Cytochrome P450 3a43 antibodyAnti-CYP3A43 antibody |
Information sourced from Uniprot.org