Anti-CYFIP2 antibody (1171-1220 aa) (STJ98613)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from CYFIP2 at the amino acid range 1171-1220
General Information
| Short Description | Rabbit polyclonal anti-Cytoplasmic FMR1-interacting protein 2 (1171-1220 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:10000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CYFIP2 |
| Gene ID | 26999 |
| Uniprot ID | CYFP2_HUMAN |
| Immunogen | Synthesized peptide derived from CYFIP2 at the amino acid range 1171-1220 |
| Immunogen Region | 1171-1220 aa |
| Specificity | CYFIP2 Polyclonal Antibody detects endogenous levels of CYFIP2 |
Additional Info
| Function | Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes. |
| Protein Name | Cytoplasmic Fmr1-Interacting Protein 2P53-Inducible Protein 121 |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-4420097Reactome: R-HSA-5663213Reactome: R-HSA-9013149Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmNucleusPerinuclear RegionSynapseSynaptosomeHighly Expressed In The Perinuclear Regionand Enriched In SynaptosomesTreatment With Leptomycin-B Triggers Translocation To The Nucleus |
| Alternative Antibody Names | Anti-Cytoplasmic Fmr1-Interacting Protein 2 antibodyAnti-P53-Inducible Protein 121 antibodyAnti-CYFIP2 antibodyAnti-KIAA1168 antibodyAnti-PIR121 antibody |
Information sourced from Uniprot.org