Anti-Cyclin A antibody (221-270 aa) (STJ92532)

SKU:
STJ92532
£48.00 - £252.00
Processing The item has been added

Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Cyclin-A1 and Cyclin-A2 (221-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCNA1
CCNA2
Gene ID: 8900
890
Uniprot ID: CCNA1_HUMAN
CCNA2_HUMAN
Immunogen Region: 221-270 aa
Specificity: Cyclin A Polyclonal Antibody detects endogenous levels of Cyclin A protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Cyclin A at the amino acid range 221-270
Post Translational Modifications Polyubiquitinated via 'Lys-11'-linked ubiquitin by the anaphase-promoting complex (APC/C), leading to its degradation by the proteasome. Deubiquitinated and stabilized by USP37 enables entry into S phase.
Function May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Protein Name Cyclin-A1
Database Links Reactome: R-HSA-1538133
Reactome: R-HSA-170145
Reactome: R-HSA-171319
Reactome: R-HSA-174184
Reactome: R-HSA-176408
Reactome: R-HSA-187577
Reactome: R-HSA-2559582
Reactome: R-HSA-2559586
Reactome: R-HSA-5689880
Reactome: R-HSA-5693607
Reactome: R-HSA-6804116
Reactome: R-HSA-6804756
Reactome: R-HSA-6804757
Reactome: R-HSA-68911
Reactome: R-HSA-68949
Reactome: R-HSA-69017
Reactome: R-HSA-69205
Reactome: R-HSA-69273
Reactome: R-HSA-69563
Reactome: R-HSA-69656
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Cyclin-A1 antibody
Anti-CCNA1 antibody

Information sourced from Uniprot.org