| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CYB5R1 |
| Gene ID: | 51706 |
| Uniprot ID: | NB5R1_HUMAN |
| Immunogen Region: | 1-305 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-305 of human CYB5R1 (NP_057327.2). |
| Immunogen Sequence: | MGIQTSPVLLASLGVGLVTL LGLAVGSYLVRRSRRPQVTL LDPNEKYLLRLLDKTTVSHN TKRFRFALPTAHHTLGLPVG KHIYLSTRIDGSLVIRPYTP VTSDEDQGYVDLVIKVYLKG VHPKFPEGGKMSQYLDSLKV GDVVEFRGPSGLLTYTGKGH FNIQPNKKSPPEPRVAKKLG MIAGGTGITPMLQLIRAILK VPEDPTQCFLLFANQTEKDI ILREDLEELQARYPNRFKL |
| Tissue Specificity | Widely expressed. |
| Function | NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. |
| Protein Name | Nadh-Cytochrome B5 Reductase 1B5r.1Humb5r2Nad(Ph -Quinone Oxidoreductase Type 3 Polypeptide A2 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-1237044 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Nadh-Cytochrome B5 Reductase 1 antibodyAnti-B5r.1 antibodyAnti-Humb5r2 antibodyAnti-Nad(Ph -Quinone Oxidoreductase Type 3 Polypeptide A2 antibodyAnti-CYB5R1 antibodyAnti-NQO3A2 antibodyAnti-UNQ3049 antibodyAnti-PRO9865 antibody |
Information sourced from Uniprot.org