| Host: | Rabbit |
| Applications: | ELISA/ICC/IF/IHC-P/IP/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-CXCR1 (272-350) is suitable for use in ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 5-.75 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:250IHC: 1:100-1:1000IF: 1:100-1:1000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | CXCR1 |
| Gene ID: | 3577 |
| Uniprot ID: | CXCR1_HUMAN |
| Immunogen Region: | 272-350 |
| Immunogen: | Synthetic peptide, corresponding to a region within C terminal amino acids 272-350 of Human CXCR1. |
| Function | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. |
| Protein Name | C-X-C Chemokine Receptor Type 1Cxc-R1Cxcr-1Cdw128aHigh Affinity Interleukin-8 Receptor AIl-8r AIl-8 Receptor Type 1Cd Antigen Cd181 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 1 antibodyAnti-Cxc-R1 antibodyAnti-Cxcr-1 antibodyAnti-Cdw128a antibodyAnti-High Affinity Interleukin-8 Receptor A antibodyAnti-Il-8r A antibodyAnti-Il-8 Receptor Type 1 antibodyAnti-Cd Antigen Cd181 antibodyAnti-CXCR1 antibodyAnti-CMKAR1 antibodyAnti-IL8RA antibody |
Information sourced from Uniprot.org