Anti-CXCL11/I-TAC nanobody [SAA1272] (STJN000035)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-C-X-C Motif Chemokine 11 is suitable for use in ELISA and RIA research applications. |
| Applications | ELISA/RIA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1272 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CXCL11 |
| Gene ID | 6373 |
| Uniprot ID | CXL11_HUMAN |
Additional Info
| Function | Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. |
| Protein Name | C-X-C Motif Chemokine 11Beta-R1H174Interferon Gamma-Inducible Protein 9Ip-9Interferon-Inducible T-Cell Alpha ChemoattractantI-TacSmall-Inducible Cytokine B11 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Nanobody Names | Anti-C-X-C Motif Chemokine 11 nanobodyAnti-Beta-R1 nanobodyAnti-H174 nanobodyAnti-Interferon Gamma-Inducible Protein 9 nanobodyAnti-Ip-9 nanobodyAnti-Interferon-Inducible T-Cell Alpha Chemoattractant nanobodyAnti-I-Tac nanobodyAnti-Small-Inducible Cytokine B11 nanobodyAnti-CXCL11 nanobodyAnti-ITAC nanobodyAnti-SCYB11 nanobodyAnti-SCYB9B nanobody |
Information sourced from Uniprot.org