Anti-CXCL10/IP-10 antibody [SAA0412] {PerCP} (STJA0029941)

SKU:
STJA0029941
$358.43 - $535.28
Free Shipping
Processing The item has been added

Host: Rat
Applications: ELISA/FC
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rat monoclonal antibody anti-C-X-C Motif Chemokine 10 is suitable for use in ELISA and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA0412
Conjugation: PerCP
Isotype: IgG1k
Formulation: 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Purification: Purified
Concentration: 0.5 mg/mL
Storage Instruction: Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol: Cxcl10
Gene ID: 15945
Uniprot ID: CXL10_MOUSE
Function Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiostatic effects. Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites. Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway, an increase in intracellular calcium production and actin reorganization. In turn, recruitment of activated Th1 lymphocytes occurs at sites of inflammation. Activation of the CXCL10/CXCR3 axis also plays an important role in neurons in response to brain injury for activating microglia, the resident macrophage population of the central nervous system, and directing them to the lesion site. This recruitment is an essential element for neuronal reorganization.
Protein Name C-X-C Motif Chemokine 10
10 Kda Interferon Gamma-Induced Protein
Gamma-Ip10
Ip-10
C7
Interferon-Gamma Induced Protein Crg-2
Small-Inducible Cytokine B10
Database Links Reactome: R-MMU-380108
Reactome: -MMU-418594
Cellular Localisation Secreted
Alternative Antibody Names Anti-C-X-C Motif Chemokine 10 antibody
Anti-10 Kda Interferon Gamma-Induced Protein antibody
Anti-Gamma-Ip10 antibody
Anti-Ip-10 antibody
Anti-C7 antibody
Anti-Interferon-Gamma Induced Protein Crg-2 antibody
Anti-Small-Inducible Cytokine B10 antibody
Anti-Cxcl10 antibody
Anti-Crg2 antibody
Anti-Ifi10 antibody
Anti-Inp10 antibody
Anti-Scyb10 antibody

Information sourced from Uniprot.org