| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | CTSW |
| Gene ID: | 1521 |
| Uniprot ID: | CATW_HUMAN |
| Immunogen Region: | 128-376 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 128-376 of human CTSW (NP_001326.2). |
| Immunogen Sequence: | VPFSCDWRKVAGAISPIKDQ KNCNCCWAMAAAGNIETLWR ISFWDFVDVSVQELLDCGRC GDGCHGGFVWDAFITVLNNS GLASEKDYPFQGKVRAHRCH PKKYQKVAWIQDFIMLQNNE HRIAQYLATYGPITVTINMK PLQLYRKGVIKATPTTCDPQ LVDHSVLLVGFGSVKSEEGI WAETVSSQSQPQPPHPTPYW ILKNSWGAQWGEKGYFRLHR GSNTCGITKFPLTARVQKP |
| Tissue Specificity | Expressed predominantly in natural killer cells, and in cytotoxic T cells. |
| Function | May have a specific function in the mechanism or regulation of T-cell cytolytic activity. (Microbial infection) Plays a role during influenza virus infection in lungs cells ex vivo. Acts at the level of virus entering host cytoplasm from late endosome. |
| Protein Name | Cathepsin WLymphopain |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-Cathepsin W antibodyAnti-Lymphopain antibodyAnti-CTSW antibody |
Information sourced from Uniprot.org