Anti-CTSK antibody (STJ11107774)

SKU:
STJ11107774
£110.50 - £505.50
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Short Description :Rabbit polyclonal Cathepsin K antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB, 1:100-1:500
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% proclin300, 50% Glycerol, pH7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CTSK
Gene ID:1513
Uniprot ID:CATK_HUMAN
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Immunogen Sequence:Human
Function Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
Protein Name Cathepsin K
Cathepsin O
Cathepsin O2
Cathepsin X
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1474228
Reactome: R-HSA-1592389
Reactome: R-HSA-1679131
Reactome: R-HSA-2132295
Reactome: R-HSA-8939242
Cellular Localisation Lysosome
Secreted
Apical Cell Membrane
Peripheral Membrane Protein
Extracellular Side
Localizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells
Alternative Antibody Names Anti-Cathepsin K antibody
Anti-Cathepsin O antibody
Anti-Cathepsin O2 antibody
Anti-Cathepsin X antibody
Anti-CTSK antibody
Anti-CTSO antibody
Anti-CTSO2 antibody

Information sourced from Uniprot.org