||WB, IHC, IF
||FOR RESEARCH USE ONLY (RUO).
||Rabbit polyclonal antibody anti-CTSE is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence.
||PBS containing 0.02% Sodium Azide, 50% Glycerol, pH7.3.
||WB 1:500-1:2000IHC 1:50-1:200IF 1:50-1:200
||Store in a freezer at-20°C and avoid freeze-thaw cycles.
||Recombinant protein of human CTSE
| Tissue Specificity || Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes. |
| Post Translational Modifications || Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide. Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57. |
| Function || May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. |
| Protein Name || Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii |
| Database Links || Reactome: R-HSA-2132295 |
| Cellular Localisation || EndosomeThe Proenzyme Is Localized To The Endoplasmic Reticulum And Golgi ApparatusWhile The Mature Enzyme Is Localized To The Endosome |
| Alternative Antibody Names || Anti-Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii antibodyAnti-CTSE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance