| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cathepsin E (243-292 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CTSE |
| Gene ID: |
1510 |
| Uniprot ID: |
CATE_HUMAN |
| Immunogen Region: |
243-292 aa |
| Specificity: |
Cathepsin E Polyclonal Antibody detects endogenous levels of Cathepsin E protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human Cathepsin E at the amino acid range 243-292 |
| Post Translational Modifications | Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide. Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57. |
| Function | May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. |
| Protein Name | Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii |
| Database Links | Reactome: R-HSA-2132295 |
| Cellular Localisation | EndosomeThe Proenzyme Is Localized To The Endoplasmic Reticulum And Golgi ApparatusWhile The Mature Enzyme Is Localized To The Endosome |
| Alternative Antibody Names | Anti-Cathepsin E Cleaved Into - Cathepsin E Form I - Cathepsin E Form Ii antibodyAnti-CTSE antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
