Anti-CTSB antibody [2A2] (STJA0021587)

SKU:
STJA0021587
£341.50 - £1,447.50
Free Shipping
Processing The item has been added

Host: Mouse
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Cathepsin B is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : 2A2
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: CTSB
Gene ID: 1508
Uniprot ID: CATB_HUMAN
Function Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis.
Protein Name Cathepsin B
App Secretase
Apps
Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain
Database Links Reactome: R-HSA-1442490
Reactome: R-HSA-1679131
Reactome: R-HSA-2022090
Reactome: R-HSA-2132295
Reactome: R-HSA-6798695
Cellular Localisation Lysosome
Melanosome
Secreted
Extracellular Space
Apical Cell Membrane
Peripheral Membrane Protein
Extracellular Side
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Localizes To The Lumen Of Thyroid Follicles And To The Apical Membrane Of Thyroid Epithelial Cells
Alternative Antibody Names Anti-Cathepsin B antibody
Anti-App Secretase antibody
Anti-Apps antibody
Anti-Cathepsin B1 Cleaved Into - Cathepsin B Light Chain - Cathepsin B Heavy Chain antibody
Anti-CTSB antibody
Anti-CPSB antibody

Information sourced from Uniprot.org