Anti-CTGF/CCN2 nanobody [SAA1211] (STJN000191)

SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
STJN000191
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General Information

Short DescriptionAlpaca monoclonal nanobody anti-Ccn Family Member 2 is suitable for use in ELISA research applications.
ApplicationsELISA
HostAlpaca
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSAA1211
IsotypeVHH-8His-Cys-tag
ConjugationUnconjugated
Concentration1 mg/mL
PurificationPurified by Nickel column.
Formulation0.01M PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Target Information

Gene SymbolCCN2
Gene ID1490
Uniprot IDCCN2_HUMAN

Additional Info

Function Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Protein Name Ccn Family Member 2
Cellular Communication Network Factor 2
Connective Tissue Growth Factor
Hypertrophic Chondrocyte-Specific Protein 24
Insulin-Like Growth Factor-Binding Protein 8
Ibp-8
Igf-Binding Protein 8
Igfbp-8
Database Links Reactome: R-HSA-2032785
Reactome: R-HSA-8951671
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Nanobody Names Anti-Ccn Family Member 2 nanobody
Anti-Cellular Communication Network Factor 2 nanobody
Anti-Connective Tissue Growth Factor nanobody
Anti-Hypertrophic Chondrocyte-Specific Protein 24 nanobody
Anti-Insulin-Like Growth Factor-Binding Protein 8 nanobody
Anti-Ibp-8 nanobody
Anti-Igf-Binding Protein 8 nanobody
Anti-Igfbp-8 nanobody
Anti-CCN2 nanobody
Anti-CTGF nanobody
Anti-HCS24 nanobody
Anti-IGFBP8 nanobody

Information sourced from Uniprot.org

Citations

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