Anti-CTGF/CCN2 nanobody [SAA1211] (STJN000191)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Ccn Family Member 2 is suitable for use in ELISA research applications. |
| Applications | ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA1211 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | CCN2 |
| Gene ID | 1490 |
| Uniprot ID | CCN2_HUMAN |
Additional Info
| Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
| Protein Name | Ccn Family Member 2Cellular Communication Network Factor 2Connective Tissue Growth FactorHypertrophic Chondrocyte-Specific Protein 24Insulin-Like Growth Factor-Binding Protein 8Ibp-8Igf-Binding Protein 8Igfbp-8 |
| Database Links | Reactome: R-HSA-2032785Reactome: R-HSA-8951671 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Nanobody Names | Anti-Ccn Family Member 2 nanobodyAnti-Cellular Communication Network Factor 2 nanobodyAnti-Connective Tissue Growth Factor nanobodyAnti-Hypertrophic Chondrocyte-Specific Protein 24 nanobodyAnti-Insulin-Like Growth Factor-Binding Protein 8 nanobodyAnti-Ibp-8 nanobodyAnti-Igf-Binding Protein 8 nanobodyAnti-Igfbp-8 nanobodyAnti-CCN2 nanobodyAnti-CTGF nanobodyAnti-HCS24 nanobodyAnti-IGFBP8 nanobody |
Information sourced from Uniprot.org